BioNMR

I (Sabieh Anwar صبیح انور ) am delivering four lectures on NMR/MRI for the biophysics course in January 2012, co-taught by Dr. Mumtaz Sheikh and Dr. Shahid Khan. On this webpage I will post the literature and ideas of term papers relevant to magnetic resonance.

Material on NMR from previous courses

• Here is a link to a series of eight lectures I gave in a course on Molecular Spectroscopy.

• Furthermore, I highly recommend watching this video from one of my lectures in the Modern Physics course, which describes in a nutshell, the physics behind the magnetic resonance phenomena. It is one hour long.

Reading material

• A copy of my presentation (week number 1).
• A copy of the presentation (week number 2).
• The most comprehensive online resource for biomedical MRI is Dr. Hornak's online book.

Ideas for term papers

I will evaluate student understanding on the basis of a term paper which should be 4-5 pages long, must describe the underlying physics and highlight the application of concepts learned in the classroom lectures to solving problems of biomedical interest. Students can work in pairs. The deadline for submitting the reports is before the mid-term. The exact date will be communicated later.

Grading will be done on the basis of:

• submitted report (both students in a group will get the same grade)
• a 10 minute long presentation by a member of the group and an oral examination (I will choose on the spot which student will deliver the presentation)

Here are some sample projects and reference material.

Paper ideas

Perfusion MRI of the cerebrum using arterial spin labelling. JMRI 13:496 (2001); Magnetom p6. (2008).	Imaging the lung void using hyperpolarized gases. Journ. Magn. Reson. Imag. 25:910 (20077); Eur. Journ. Radiol. 40:33 (2001).	Cardiovascular angiography using magnetic resonance. Canad. Med. Assoc. Journ. 175:911 (2006).	Single cell MRI. Magn. Reson. Med. 55:242 (2006); Nature Clin. Pract. 3:554 (2006).	Studying protein folding using NMR. Nature Struct. Biol. 4:10 (1997); Chem. Rev. 104:3607 (2004).	Chemical analysis, cell tracking and disease detection using lab-on-a-chip NMR. Anal. Bioanal. Chem. 385:416 (2006); Anal. Chem. 77:8109 (2005).
Dual-modality imaging using MRI and PET (Positron emission tomography) Nature Med. 14:459 (2008); Trends Mol. Med. 16:508 (2010).	Nanoparticles for MRI based targeted drug delivery Adv. Drug Delivery 60:1252 (2008); Magn. Reson. Med. 51:1153 (2004).	Xenon NMR niosensors for disease detection. Journ. Amer. Chem. Soc. 126:15287 (2004); Angew. Chemie. Int. Ed. 118:76 (2006).